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Nanotechnology Innovation Center of Kansas State

Dr Deryl Troyer

troyerProfessor

Degrees

D.V.M., Kansas State University

Ph.D., Kansas State University

Contact

785-532-4509

troyer@vet.ksu.edu

Research

Improved targeting of cancer therapy, cancer detection, and improved animal models. Nanotechnology research is a key component in these objectives.

Major Equipment

ZetaPALS (Brookhaven) dynamic light scattering apparatus. A Guava Easycyte PLUS benchtop flow cytometer with multicolor antigen detection. Two magnetic hyperthermia systems, one 336 kHz, one 100 kHz output frequency.  

Publications

Basel M, Balivada S, Shreshta T, Seo G, Pyle M, Bossmann S, Troyer D: A cell-delivered and activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer model. Small 8(6):913-920, 2012. 

Basel M, Balivada S, Wang H, Shrestha T, Seo G, Pyle M, Abayaweera G, Daini R, Koper O, Tamura M, Chikan V, Bossmann S, Troyer D: Cell-delivered magnetic nanoparticles causes hyperthermia-mediated increased survival in a murine pancreatic cancer model. Int. J.of Nanomedicine 7:297-306, 2012.

Basel MT, Shrestha T, Troyer D, Bossmann SH: Protease-sensitive, polymer-caged liposomes: a method for making highly targeted liposomes using triggered release. ACS Nano 5(3):2162-2175, 2011.

Seo G-M, Rachakatla R, Balivada S, Pyle M, Shrestha T, Wang H, Tamura M, Bossmann S, Troyer DL: A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma. Mol. Biol. Rep. 39(1):157-165, 2011.

Rachakatla R, Balivada S, Seo G, Myers C, Wang H, Samarakoon T, Dani R, Pyle M, Kroh F, Walker B, Leaym X, Koper O, Chikan V, Bossmann S, Tamura M, Troyer D: Attenuation of mouse melanoma by A/C magnetic field after delivery of bi-magnetic nanoparticles by neural progenitor cells. ACS Nano.

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