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Nanotechnology Innovation Center of Kansas State

Jeffrey Robert Comer

Jeffrey Robert ComerAssistant Professor


B.S. Physics, University of Akron, OH
Ph.D. Physics, University of Akron, OH


The interface between nanotechnology and biology and the transport phenomena in living systems. Also, interested in the kinetics of biomolecules, free energy calculations, and protein-nucleic acid interactions.


DeLong RK, Mitchell JA, Morris RT, Comer J, Hurst MN, Ghosh K, Wanekaya A, Mudge M, Schaeffer A, Washington LL, Risor-Marhanka A, Thomas S, Marroquin S, Lekey A, Smith JJ, Garrad R, Aryal S, Abdelhakiem M, Glaspell GP. Enzyme and cancer cell selectivity of nanoparticles: inhibition of 3-d metastatic phenotype and experimental melanoma by zinc oxide” J Biomed Nanotechnol 13, 221-231, 2017.

Lee C, Comer J, Herndon C, Leung N, Pavlova A, Swift R, Tung C, Rowley CN, Amaro R, Chipot C, Wang Y, Gumbart JC. Simulation-based approaches for determining membrane permeability of small compounds. J. Chem. Inf. Model. 56 (4): 721–733, 2016.

Comer J, Aksimentiev A.  DNA sequence-dependent ionic currents in ultra-small solid-state nanopores. Nanoscale 8 (18): 9600–9613, 2016.

Poblete H, Agarwal A, Thomas S, Bohne C, Ravichandran R, Phospase  J, Comer J, Alarcon EI.  New insights into peptide-silver nanoparticle interaction: deciphering the role of cysteine and lysine in the peptide sequence.  Langmuir 32:265-273, 2016.

Zoonens M, Comer J, Masscheleyn S, Pebay-Peyroula E, Chipot CJ, Miroux B, Dehez F. Dangerous liaisons between detergents and membrane proteins. the case of mitochondrial uncoupling protein 2. JAmChemSoc 135(40):15174-15182, 2013.

Carrasco-Sanchez V, Vergara-Jaque A, Zuniga M, Comer J, Amalraj J, Nachtigall FM, Lizama OV,Duran-Lara E,Sandoval C, Santos LS. Insitu and in silico evaluation of amine-andfolate-terminated dendrimers as nanocarriers of anesthetics. EurJMedChem.doi:10.1016/j.ejmech.2013.11.040., 2013

Chaudhry JH ,Comer J,Aksimentiev A, Olson LN. A stabilized finite element method for modified Poisson-Nernst-Planck equations to determine ion
flow through a nanopore. CommunComputPhys15:93125. doi:10.4208/cicp.101112.100413a, 2014.

Vergara-Jaque A, Comer J, Monsalve L,Gonzalez-Nilo FD, Sandoval C. A computationally efficient methodology for atomic-level characterization of dendrimer drug complexes:Comparison of amine-and acetyl-terminated PAMAM. JPhysChemB117(22):6801,2013.

Vilos C, Morales FA, Solar PA, Herrera NS,Gonzalez-Nilo FD, Aguayo DA, Mendoza HL,Comer J, Bravo ML, Gonzalez PA, Kato S, Cuello MA, Alonso C, Bravo EJ, Bustamante EI, Owend GI, Velasquez LA. Paclitaxel-PHBVnanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials34(16):4098-4108, 2013.

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